Harvard and Mass. General Hospital clinical trial showed Lief as an adjunct to typical SUD treatment decreases substance use by an additional 64%.







Lief has been used by thousands of patients to alleviate symptoms of stress and manage substance use cravings.
For patients receiving SUD treatment, Lief helps preemptively reduce negative affect and weaken the connection between craving and subsequent use.
See the importance of heart rate variability biofeedback (HRVB) on mental health outcomes from these top-tier, peer-reviewed journals.

Lief's unique in-the-moment HRV biofeedback reduces relapse, craving & negative affect, decreasing AOD use days 64%.
See JAMA Psych study on substance use and relapse →
Heart rate variability biofeedback (HRVB) improves mental health outcomes.
Meta-analysis: HRVB for stress & anxiety →
Heart rate variability biomarkers help assess mental health.
See study on anxiety & heart rate variability →See study on depression & heart rate variability →Cost effectively extend your primary care team with dedicated LiefRx behavioral health coaches, telepsychiatrists, and billing specialists.


LiefRx's billing specialists help ensure the program is cost effective for your clinic and your patients.
We'll reach out to you with more information on the Lief Program, device and billing options. Let us know how to get in touch.
