for SuD Healthcare Providers
64% fewer alcohol and drug use days
A Harvard-led clinical trial found Lief reduced craving, substance use and negative emotions among individuals in early recovery from SUD.
JAMA Psychiatry, 2025
A Harvard-led clinical trial found Lief reduced craving, substance use and negative emotions among individuals in early recovery from SUD.
In a randomized clinical trial conducted by Harvard and Mass. General Hospital, real-time HRV biofeedback weakened the link between craving and subsequent substance use.
When craving was strongest, participants using Lief were five times less likely to use alcohol or drugs.
See the importance of heart rate variability biofeedback (HRVB) on mental health outcomes from these top-tier, peer-reviewed journals.
Lief's unique in-the-moment HRV biofeedback reduced relapse, craving & negative affect, decreasing AOD use days 64%.
See JAMA Psych study on substance use and relapse →
Heart rate variability biofeedback (HRVB) improves mental health outcomes.
Meta-analysis: HRVB for stress & anxiety →
Heart rate variability biomarkers help assess mental health.
Meta-analysis: anxiety & heart rate variability →Meta-analysis: depression & heart rate variability →Cost effectively extend your primary care team with dedicated LiefRx behavioral health coaches, telepsychiatrists, and billing specialists.
LiefRx's billing specialists help ensure the program is cost effective for your clinic and your patients.
We'll reach out to you with more information on the Lief Program, device and billing options. Let us know how to get in touch.
